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This lesson gives an introduction to high-performance computing with the Compute Canada network, first providing an overview of use cases for HPC and then a hands-on tutorial. Though some examples might seem specific to the Calcul Québec, all computing clusters in the Compute Canada network share the same software modules and environments.

Difficulty level: Beginner
Duration: 02:49:34

This talk presents an overview of CBRAIN, a web-based platform that allows neuroscientists to perform computationally intensive data analyses by connecting them to high-performance computing facilities across Canada and around the world.

Difficulty level: Beginner
Duration: 56:07
Speaker: : Shawn Brown

This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

In this tutorial on simulating whole-brain activity using Python, participants can follow along using corresponding code and repositories, learning the basics of neural oscillatory dynamics, evoked responses and EEG signals, ultimately leading to the design of a network model of whole-brain anatomical connectivity. 

Difficulty level: Intermediate
Duration: 1:16:10
Speaker: : John Griffiths

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Difficulty level: Intermediate
Duration: 1:28:14

Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks. 

Difficulty level: Intermediate
Duration: 6:00
Speaker: : Marcus Ghosh

This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems. 

Difficulty level: Intermediate
Duration: 12:52
Speaker: : Dan Goodman

This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks. 

Difficulty level: Intermediate
Duration: 50:44
Speaker: : Caterina Gratton

This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.

Difficulty level: Advanced
Duration: 50:28
Speaker: : Pierre Bellec
Course:

Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.

Neuronify aims to provide a low entry point to simulation-based neuroscience.

Difficulty level: Beginner
Duration: 01:25
Speaker: : Neuronify

This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.

Difficulty level: Beginner
Duration: 14:24
Speaker: : Heidi Kleven

This lesson provides a tutorial on how to handle writing very large data in MatNWB. 

Difficulty level: Advanced
Duration: 16:18
Speaker: : Ben Dichter

This lesson provides an overview of the CaImAn package, as well as a demonstration of usage with NWB.

Difficulty level: Intermediate
Duration: 44:37

This lesson gives an overview of the SpikeInterface package, including demonstration of data loading, preprocessing, spike sorting, and comparison of spike sorters.

Difficulty level: Intermediate
Duration: 1:10:28
Speaker: : Alessio Buccino

In this lesson, users will learn about the NWBWidgets package, including coverage of different data types, and information for building custom widgets within this framework.

Difficulty level: Intermediate
Duration: 47:15
Speaker: : Ben Dichter

This video explains what metadata is, why it is important, and how you can organize your metadata to increase the FAIRness of your data on EBRAINS.

Difficulty level: Beginner
Duration: 17:23
Speaker: : Ulrike Schlegel

This lecture provides reviews some standards for project management and organization, including motivation from the view of the FAIR principles and improved reproducibility.

Difficulty level: Beginner
Duration: 01:08:34
Speaker: : Elizabeth DuPre

This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system. 

Difficulty level: Intermediate
Duration: 4:10
Speaker: : Dan Goodman

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

Difficulty level: Intermediate
Duration: 9:34
Speaker: : Dan Goodman

This lecture discusses the FAIR principles as they apply to electrophysiology data and metadata, the building blocks for community tools and standards, platforms and grassroots initiatives, and the challenges therein.

Difficulty level: Beginner
Duration: 8:11
Speaker: : Thomas Wachtler