The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity.
This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health.
This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment.
This lesson corresponds to slides 1-64 in the PDF below.
This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.
Introduction of the Foundations of Machine Learning in Python course - Day 01.
High-Performance Computing and Analytics Lab, University of Bonn
Optimization for machine learning - Day 02 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Linear Algebra for Machine Learning - Day 03 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Support Vector Machines - Day 06 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Decision Trees and Random Forests - Day 07 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Clustering and Density Estimation - Day 08 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Dimensionality Reduction - Day 09 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Introduction to Neural Networks - Day 10 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Introduction to Convolutional Neural Networks - Day 11 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn