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The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

Difficulty level: Beginner
Duration: 1:29:28

This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.

Difficulty level: Beginner
Duration: 1:16:04

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

Difficulty level: Beginner
Duration: 52:26

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

Difficulty level: Beginner
Duration: 1:20:28
Speaker: : Abhi Pratap

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

Difficulty level: Intermediate
Duration: 1:28:16
Speaker: : Dan Felsky

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

Difficulty level: Intermediate
Duration:
Speaker: : Dan Felsky

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

Difficulty level: Intermediate
Duration: 1:29:08

This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health. 

Difficulty level: Intermediate
Duration: 1:47:22

This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment. 

This lesson corresponds to slides 1-64 in the PDF below. 

Difficulty level: Intermediate
Duration: 1:28:14

This lecture provides an introduction to Plato’s concept of rationality and Aristotle’s concept of empiricism, and the enduring discussion between rationalism and empiricism to this day.

Difficulty level: Beginner
Duration: 1:13:45

This lecture covers different perspectives on the study of the mental, focusing on the difference between Mind and Brain. 

Difficulty level: Beginner
Duration: 1:16:30

This lecture goes into further detail about the hard problem of developing a scientific discipline for subjective consciousness.

Difficulty level: Beginner
Duration: 58:03

This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.

Difficulty level: Beginner
Duration: 2:24:35

This lesson gives a brief introduction to the course Neuroscience for Machine Learners (Neuro4ML). 

Difficulty level: Beginner
Duration: 1:25
Speaker: : Dan Goodman

This lesson briefly goes over the outline of the Neuroscience for Machine Learners course. 

Difficulty level: Intermediate
Duration: 3:05
Speaker: : Dan Goodman

This lesson covers the history of neuroscience and machine learning, and the story of how these two seemingly disparate fields are increasingly merging. 

Difficulty level: Beginner
Duration: 12:25
Speaker: : Dan Goodman

In this lesson, you will learn about the current challenges facing the integration of machine learning and neuroscience. 

Difficulty level: Beginner
Duration: 5:42
Speaker: : Dan Goodman

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

Difficulty level: Intermediate
Duration: 7:03
Speaker: : Marcus Ghosh

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

Difficulty level: Intermediate
Duration: 4:48
Speaker: : Marcus Ghosh

This lesson delves into the human nervous system and the immense cellular, connectomic, and functional sophistication therein. 

Difficulty level: Intermediate
Duration: 8:41
Speaker: : Marcus Ghosh