Brain medicine for non-specialists

14 parts

HBP Curriculum: Interdisciplinary Brain Science. Brain medicine for non-specialists

The human mind is a complex system that produces, processes and transmits information in an incomparable manner. Human thoughts and actions depend profoundly on the proper function of neurons. If this function is disrupted, degeneration and disease can be the consequence. This course provides insights into state-of-the-art views on neurodegenerative, neuropsychiatric and neuroimmunological disorders as well as clinical neuroanatomy and clinical aspects of brain imaging. Apart from the scientific understanding of specific disorders and their treatment, it also discusses the latest findings in research and therapeutics. The Medical Informatics Platform developed in the European Human Brain Project is introduced with an example of how a big data approach may have the potential to improve diagnosis and therapeutic concepts of neurological diseases. Contributions for this course come from renowned researchers and clinicians from Israel, Austria and Switzerland.

The natural history of neurodegenerative disease I

This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases. Speaker: Nir Giladi.

The natural history of neurodegenerative disease II

This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases. Speaker: Nir Giladi.

Clinical neuroanatomy: From a lesion to a symptom I

This lecture will discuss how understanding and applying simple neuroanatomical rules, one can localize the damage along the neuroaxis, the first crucial step toward making the correct clinical diagnosis and initiating treatment. Speaker: Eitan Auriel.

Clinical neuroanatomy: From a lesion to a symptom II

This lecture will discuss how understanding and applying simple neuroanatomical rules, one can localize the damage along the neuroaxis, the first crucial step toward making the correct clinical diagnosis and initiating treatment. Speaker: Eitan Auriel.

Neuroimmunology: The brain as a cognitive antigen

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss. Speaker: Anat Achiron.

Motivation and addiction: Neuronetworks and treatment targets

Most psychiatric disorders (most notably dependence syndromes, depression, psychosis, and autism) are characterized by impaired social interaction, with many patients preferring a drug of abuse. This lecture focuses on the latest research on the neural basis of normal and impaired social interaction. Speaker: Gerald Zernig.

Clinical aspects of brain imaging I

This lecture will provide an overview of neuroimaging techniques and their clinical applications. Speaker: Dafna Ben Bashat.

Clinical aspects of brain imaging II

This lecture will provide an overview of neuroimaging techniques and their clinical applications. Speaker: Dafna Ben Bashat.

Neurodegenerative disease: En route to early detection and prevention

This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases. Speaker: Nir Giladi.

Introduction to schizophrenia

A basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options. Speaker: Wolfgang Fleischhacker.

Affective disorders: depression and somatic co-morbidity

This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options. Speaker: Barbara Sperner-Unterweger.

A manic depressive history: The genetic dissection of complex neuropsychiatric disorders

How genetics can contribute to our understanding of psychiatric phenotypes. Speaker: Sven Cichon.

HBP Medical Informatics Platform: Parkinson‘s disease & more…

The lecture focuses on rationale for employing neuroimaging methods for movement disorders. Speaker: Bogdan Draganski.

Principles of neuropharmacology

An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System. Speaker: Sandra Santos-Sierra.